Tag: cgmp

Believe it or not, curcumin (the most famous chemical and anti-inflammatory derived from turmeric root used in asian cooking) could be more effective than sildenafil. Check out this pub med study Efficacy of a novel water-soluble curcumin derivative versus sildenafil citrate in mediating erectile function.

In conclusion, NCD (Novel Curcumin Derivative) could enhance erectile function with more efficacy and more prolonged duration of action.

Here’s another study that says it can be effective for up to a week vs a few hours for Viagra.
You can read it here.

Results. In group 2, there was a significant progressive maintained elevation of HO activity and cGMP tissue levels
starting from the first hour in subgroups 3 and 4, whereas, the rise in HO activity and cGMP started from second
hour regarding the other rat subgroups. Sildenafil effect decreased after 3 hours. In group 3, there was a significant
maintained elevation of HO activity and cGMP tissue levels extended to 1 week as compared to controls for all rat
subgroups that received both forms of curcumin. In group 4, long-acting curcumin derivative exhibited more
significant potentiation of intracavernosal pressure as compared to control and to the pure curcumin.
Conclusion. Water-soluble long-acting curcumin derivative could mediate erectile function via upregulating cavernous
tissue cGMP.

I’ve been looking for a water soluble curcumin supplement. They are hard to find, but this looks like an early one: